In looking at my Postfix mail.logs, I only see the new ICANN vanity gTLDs really generating garbage spam. Lots of press on the mess this all is causing. I got kind of sick of even dealing with that, so here is the header_checks lines I use to block them via postfix if you want to do that on your setup. There are a lot of articles on the internet for this, but I here is what works for me. YMMV.
Add these lines to your active header_checks file and swap the TLD with the ones you want to block. You probably will be okay blocking the ones I have below though too.
/^Received: .*\.party .*$/ REJECT Stop it.
/^Received: .*\.stream .*$/ REJECT Stop it.
/^Received: .*\.review .*$/ REJECT Stop it.
/^Received: .*\.science .*$/ REJECT Stop it.
/^Received: .*\.local .*$/ REJECT Stop it.
/^Received: .*\.loan .*$/ REJECT Stop it.
/^Received: .*\.trade .*$/ REJECT Stop it.
/^Received: .*\.bid .*$/ REJECT Stop it.
These patterns work on header_check files nicely to nix some of the bogus email inbound with calls to these TLDs.